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KMID : 1039420190530020112
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Journal of Pathology and Translational Medicine
2019 Volume.53 No. 2 p.112 ~ p.118
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Squamous Cell Carcinoma of the Extrahepatic Common Hepatic Duct
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Kang Myung-Hee
Kim Na-Rae
Chung Dong-Hae
Cho Hyun-Yee
Park Yeon-Ho
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Abstract
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We report a rare case of hilar squamous cell carcinoma. A 62-year-old Korean woman complaining of nausea was referred to our hospital. Her biliary computed tomography revealed a 28 mm-sized protruding solid mass in the proximal common bile duct. The patient underwent left hemihepatectomy with S1 segmentectomy and segmental excision of the common bile duct. Microscopically, the tumor was a moderately differentiated squamous cell carcinoma of the extrahepatic bile duct, without any component of adenocarcinoma or metaplastic portion in the biliary epithelium. Immunohistochemically, the tumor was positive for cytokeratin (CK) 5/6, CK19, p40, and p63. Squamous cell carcinoma of the extrahepatic bile duct is rare. To date, only 24 cases of biliary squamous cell carcinomas have been reported. Here, we provide a clinicopathologic review of previously reported extrahepatic bile duct squamous cell carcinomas.
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KEYWORD
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Carcinoma, squamous cell, Klatskin tumor, Hepatic duct, common, Hilum, Chemotherapy
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